January 21, 2002
Heartburn Relief in 20 Days?
New Natural Product From Enzymatic Therapy
Provides Promising, Lasting Results on Occasional Heartburn in Clinical
- First there was the purple pill, now there is the orange
pill. Correction: orange peel, as in orange peel extract (OPE). In an
interesting turn of events, a fruit once considered a no-no for heartburn
sufferers -- the orange -- is now being heralded as a potential long-term
remedy in a multi-billion dollar industry.
Recent tests indicate OPE, or more specifically, a key ingredient called
d-Limonene which naturally occurs in citrus and a wide variety of other
plant species, can prevent occasional heartburn, greatly reducing the number
of occasional heartburn incidents.
There are two theories regarding how OPE works:
1) OPE may promote healthy peristalsis, the normal function of the body to
move food and fluid from one place to another.
2) OPE may work as a surfactant, reducing the surface tension of the
liquid contents in the stomach
Researchers have applied for a patent for Heartburn Free(TM), a proprietary
20-day preventative regimen shown in a clinical trial to provide relief to
nearly 90 percent of participants by day 14.(1)
Enzymatic Therapy of Green Bay, Wis. began distributing the product to
health food stores in December. Heartburn Free is the first heartburn
product with OPE. The OPE used in Heartburn Free is standardized to contain
a minimum of 98.5% d-limonene.
While there may be immediate positive effects on occasional heartburn
starting with the first dose, the full regimen results in optimal, long
lasting relief -- relief that lasts well beyond the last dose on day 20.
Additional research is ongoing to determine just how long the positive
"Heartburn Free is unique because it actually addresses the underlying cause
of occasional heartburn, rather than simply masking symptoms," said Dr.
Decker Weiss, a naturopathic physician and member of the Enzymatic Therapy
Scientific Advisory Board. "Further, it does not interfere with healthy
stomach acid levels nor does it inhibit mineral absorption or protein
digestion, problems related to use of other heartburn products."
Even though occasional heartburn itself is not considered a disease,
heartburn is often quite distressing, accounting for significant pain and
discomfort. As many as 60 million Americans experience heartburn at least
once a month. Heartburn Free is not intended for persistent or chronic
heartburn, which is a serious condition for which a health care professional
should be consulted.
Existing treatment options, such as antacids, proton pump inhibiters, H2
blockers and even surgery, may help chronic sufferers, but often interfere
with healthy stomach acid levels and mineral absorption or protein
digestion. Until now, the options have been limited: either live with the
burning, or live with diarrhea, constipation, headache, nausea, drowsiness,
muscle spasms, depression and the other potential side effects of
Since Terry Lemerond founded the company in 1981, Enzymatic Therapy has
introduced some unique firsts to the U.S. health market including Ginkgo
Biloba and Glucosamine Sulfate. More recently, Enzymatic Therapy introduced
a number of clinically studied and immensely popular products including
Vitaline(R) CoQ10 and Eskimo-3(R), and scientifically based, proprietary
formulas, such as Cell Forte(R) with IP-6 and Inositol, 7-Keto(TM)
Naturalean and Indolplex(R).
Enzymatic Therapy Inc. is comprised of Enzymatic Therapy and Integrative
Therapeutics. Enzymatic Therapy distributes the Enzymatic Therapy and
Prevail brands to health food stores and the PhytoPharmica brand to
pharmacies. Integrative Therapeutics distributes PhytoPharmica, Tyler, NF
Formulas and Vitaline brands to health care professionals. Integrative
Therapeutics is the largest manufacturer of professional-line dietary
supplements in the industry.
(1) Wilkins J, Heggers J, Willette R, Wilkins JS. Relief of heartburn
naturally. Unpublished data. Wilkins Research, Galveston Texas.
(2) National Heartburn Alliance. Get Heartburn Smart: Self-Care Strategies
for Heartburn Sufferers (brochure).