On October 16, 2000, Wyeth-Ayerst Laboratories, a division of American
Home Products Corporation (NYSE:AHP), voluntarily recalled 50 specific lots of Premarin®
(conjugated estrogens tablets, USP) and one lot of Premphase® (conjugated estrogens/
medroxyprogesterone acetate tablets), distributed in the United States. In routine quality
assurance testing, Wyeth-Ayerst identified lots that did not meet current USP dissolution
recall is limited to specific lots of Premarin® 0.625 mg, 0.9 mg, 1.25 mg, and 2.5 mg and
Premphase that are currently at wholesalers. It does not affect Premarin or
Premphase in retail pharmacy outlets or product that women may have in their possession.
Women who take Premarin or Premphase from these
specified lots receive the appropriate prescribed estrogen dose. These products are
effective for the treatment of moderate to severe menopausal symptoms such as hot flashes,
night sweats, and vaginal dryness, and for the prevention of osteoporosis.
As always, if women have questions, they should
contact their health care provider, or they can call Wyeth-Ayerst Medical Affairs at
1-800-934-5556 from 8:30 a.m. to 4:30 p.m. ET.
As a leader in womens health care,
Wyeth-Ayerst takes its responsibility to women very seriously and is dedicated to
providing the highest quality products.
Products in the Premarin® family have been used
safely and effectively for nearly 60 years by millions of women to help relieve the
symptoms of menopause, and to prevent osteoporosis.